16.05.2018

Buy Twinvir online

Twinvir ™ — combined antiviral agent.

Composition

One Twinvir ™ Buy Twinvir online contains Ladipasvir 90 mg and Sophosbuvir 400 mg.

Indication

The combination of Ledipasvir and Sofosbuvir is used for the treatment of hepatitis C of genotype 1, 4, 5 and 6 in adults.

Dosage Form

28 tablets, film-coated.

Dosage and Administration

Recommended dosage: one tablet (Ladipasvir 90 mg and Sofosbuvir 400 mg) is taken orally once a day. Recommended duration of treatment for patients without experience of negative response to therapy: 12 weeks. With experience of a negative response to therapy (without cirrhosis of the liver): 24 weeks. With experience of a negative response to therapy (with cirrhosis of the liver): 24 weeks.

Drug Interactions

P-gp inductors (rifampicin, rifabutin, St. John’s wort, carbmazepine, phenobarbital and phenytoin) lower the concentration of Ladipasvir and Sofosbuvir in the blood, which adversely affects the effectiveness of treatment.

Pregnancy and Lactation

There is no data on the effect of the drug on fetal development and lactation. During pregnancy and breastfeeding, the drug can be prescribed only by the therapist.

Pediatrics

The safety and efficacy of the combination of Ledipasvir and Sofosbuvir in patients under 18 years of age have not been studied.

Description

Twinvir ™ is available in the form of tablets for oral administration. The composition includes two active components: Ladipasvir, which is an inhibitor of the viral protein, and also Sofosbuvir, an inhibitor of the RNA polymerase.

Special Instructions

The joint administration of amiodarone with the combination of Ledipasvir and Sofosbuvirais not recommended. Cardiac monitoring is recommended in patients without alternative treatment options. The use of Twinvir ™ with other drugs containing Sofosbuvir is not recommended.

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